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Role of CpG deserts in the epigenetic transgenerational inheritance of differential DNA methylation regions

BACKGROUND: Previously a variety of environmental toxicants were found to promote the epigenetic transgenerational inheritance of disease through differential DNA methylation regions (DMRs), termed epimutations, present in sperm. The transgenerational epimutations in sperm and somatic cells identifi...

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Bibliografiske detaljer
Main Authors: Skinner, Michael K, Guerrero-Bosagna, Carlos
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149044/
https://ncbi.nlm.nih.gov/pubmed/25142051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-692
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