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Role of CpG deserts in the epigenetic transgenerational inheritance of differential DNA methylation regions

BACKGROUND: Previously a variety of environmental toxicants were found to promote the epigenetic transgenerational inheritance of disease through differential DNA methylation regions (DMRs), termed epimutations, present in sperm. The transgenerational epimutations in sperm and somatic cells identifi...

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Detalhes bibliográficos
Main Authors: Skinner, Michael K, Guerrero-Bosagna, Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149044/
https://ncbi.nlm.nih.gov/pubmed/25142051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-692
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