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Role of CpG deserts in the epigenetic transgenerational inheritance of differential DNA methylation regions

BACKGROUND: Previously a variety of environmental toxicants were found to promote the epigenetic transgenerational inheritance of disease through differential DNA methylation regions (DMRs), termed epimutations, present in sperm. The transgenerational epimutations in sperm and somatic cells identifi...

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Autors principals: Skinner, Michael K, Guerrero-Bosagna, Carlos
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149044/
https://ncbi.nlm.nih.gov/pubmed/25142051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-692
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