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A CUL-2 ubiquitin ligase containing three FEM proteins degrades TRA-1 to regulate C. elegans sex determination

In Caenorhabditis elegans, the Gli-family transcription factor TRA-1 is the terminal effector of the sex determination pathway. TRA-1 activity inhibits male development and allows female fates. Genetic studies have indicated that TRA-1 is negatively regulated by the fem-1, fem-2, and fem-3 genes. Ho...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Starostina, Natalia G., Lim, Jae-min, Schvarzstein, Mara, Wells, Lance, Spence, Andrew M., Kipreos, Edward T.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2007
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064902/
https://ncbi.nlm.nih.gov/pubmed/17609115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2007.05.008
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