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uPAR induces epithelial–mesenchymal transition in hypoxic breast cancer cells
Hypoxia activates genetic programs that facilitate cell survival; however, in cancer, it may promote invasion and metastasis. In this study, we show that breast cancer cells cultured in 1.0% O(2) demonstrate changes consistent with epithelial–mesenchymal transition (EMT). Snail translocates to the n...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Rockefeller University Press
2007
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2064849/ https://ncbi.nlm.nih.gov/pubmed/17664334 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200701092 |
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