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uPAR induces epithelial–mesenchymal transition in hypoxic breast cancer cells

Hypoxia activates genetic programs that facilitate cell survival; however, in cancer, it may promote invasion and metastasis. In this study, we show that breast cancer cells cultured in 1.0% O(2) demonstrate changes consistent with epithelial–mesenchymal transition (EMT). Snail translocates to the n...

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Bibliografiska uppgifter
Huvudupphovsmän: Lester, Robin D., Jo, Minji, Montel, Valérie, Takimoto, Shinako, Gonias, Steven L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2007
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064849/
https://ncbi.nlm.nih.gov/pubmed/17664334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200701092
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