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Cell size and invasion in TGF-β–induced epithelial to mesenchymal transition is regulated by activation of the mTOR pathway

Epithelial to mesenchymal transition (EMT) occurs during development and cancer progression to metastasis and results in enhanced cell motility and invasion. Transforming growth factor-β (TGF-β) induces EMT through Smads, leading to transcriptional regulation, and through non-Smad pathways. We obser...

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Bibliografske podrobnosti
Main Authors: Lamouille, Samy, Derynck, Rik
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064840/
https://ncbi.nlm.nih.gov/pubmed/17646396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200611146
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