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Cell size and invasion in TGF-β–induced epithelial to mesenchymal transition is regulated by activation of the mTOR pathway

Epithelial to mesenchymal transition (EMT) occurs during development and cancer progression to metastasis and results in enhanced cell motility and invasion. Transforming growth factor-β (TGF-β) induces EMT through Smads, leading to transcriptional regulation, and through non-Smad pathways. We obser...

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Autors principals: Lamouille, Samy, Derynck, Rik
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064840/
https://ncbi.nlm.nih.gov/pubmed/17646396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200611146
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