Dephosphorylation of survival motor neurons (SMN) by PPM1G/PP2Cγ governs Cajal body localization and stability of the SMN complex

The survival motor neuron (SMN) complex functions in maturation of uridine-rich small nuclear ribonucleoprotein (RNP) particles. SMN mediates the cytoplasmic assembly of Sm proteins onto uridine-rich small RNAs, and then participates in targeting RNPs to nuclear Cajal bodies (CBs). Recent studies ha...

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Detalhes bibliográficos
Main Authors: Petri, Sebastian, Grimmler, Matthias, Over, Sabine, Fischer, Utz, Gruss, Oliver J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2007
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064792/
https://ncbi.nlm.nih.gov/pubmed/17984321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200704163
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