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The human checkpoint Rad protein Rad17 is chromatin-associated throughout the cell cycle, localizes to DNA replication sites, and interacts with DNA polymerase ε

The checkpoint Rad proteins Rad17, Rad9, Rad1, Hus1, ATR, and ATRIP become associated with chromatin in response to DNA damage caused by genotoxic agents and replication inhibitors, as well as during unperturbed DNA replication in S phase. Here we show that murine Rad17 is phosphorylated at two site...

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Détails bibliographiques
Auteurs principaux: Post, Sean M., Tomkinson, Alan E., Lee, Eva Y.-H. P.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2003
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC206465/
https://ncbi.nlm.nih.gov/pubmed/14500819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkg765
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