High levels of Notch signaling down-regulate Numb and Numblike

Inhibition of Notch signaling by Numb is critical for many cell fate decisions. In this study, we demonstrate a more complex relationship between Notch and the two vertebrate Numb homologues Numb and Numblike. Although Numb and Numblike at low levels of Notch signaling negatively regulated Notch, hi...

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Main Authors: Chapman, Gavin, Liu, Lining, Sahlgren, Cecilia, Dahlqvist, Camilla, Lendahl, Urban
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2006
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064589/
https://ncbi.nlm.nih.gov/pubmed/17116748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200602009
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