CD98hc (SLC3A2) participates in fibronectin matrix assembly by mediating integrin signaling

Integrin-dependent assembly of the fibronectin (Fn) matrix plays a central role in vertebrate development. We identify CD98hc, a membrane protein, as an important component of the matrix assembly machinery both in vitro and in vivo. CD98hc was not required for biosynthesis of cellular Fn or the main...

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Bibliographic Details
Main Authors: Féral, Chloé C., Zijlstra, Andries, Tkachenko, Eugene, Prager, Gerald, Gardel, Margaret L., Slepak, Marina, Ginsberg, Mark H.
Format: Artigo
Language:Inglês
Published: Rockefeller University Press|1 2007
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064475/
https://ncbi.nlm.nih.gov/pubmed/17682053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200705090
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