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CD98hc (SLC3A2) participates in fibronectin matrix assembly by mediating integrin signaling
Integrin-dependent assembly of the fibronectin (Fn) matrix plays a central role in vertebrate development. We identify CD98hc, a membrane protein, as an important component of the matrix assembly machinery both in vitro and in vivo. CD98hc was not required for biosynthesis of cellular Fn or the main...
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| Главные авторы: | , , , , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Rockefeller University Press|1
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2064475/ https://ncbi.nlm.nih.gov/pubmed/17682053 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200705090 |
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