CD98hc (SLC3A2) drives integrin-dependent renal cancer cell behavior

BACKGROUND: Overexpression of CD98hc (SLC3A2) occurs in a variety of cancers and is suspected to contribute to tumor growth. CD98, a heterodimeric transmembrane protein, physically associates with certain integrin β subunit cytoplasmic domains via its heavy chain, CD98hc. CD98hc regulates adhesion-i...

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Detalhes bibliográficos
Main Authors: Poettler, Marina, Unseld, Matthias, Braemswig, Kira, Haitel, Andrea, Zielinski, Christoph C, Prager, Gerald W
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3879186/
https://ncbi.nlm.nih.gov/pubmed/24359579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-12-169
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