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Conformational changes in the GTPase modules of the signal reception particle and its receptor drive initiation of protein translocation

During cotranslational protein targeting, two guanosine triphosphatase (GTPase) in the signal recognition particle (SRP) and its receptor (SR) form a unique complex in which hydrolyses of both guanosine triphosphates (GTP) are activated in a shared active site. It was thought that GTP hydrolysis dri...

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Detalles Bibliográficos
Main Authors: Shan, Shu-ou, Chandrasekar, Sowmya, Walter, Peter
Formato: Artigo
Idioma:Inglês
Publicado: Rockefeller University Press|1 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064468/
https://ncbi.nlm.nih.gov/pubmed/17682051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200702018
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