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Sequential activation of human signal recognition particle by the ribosome and signal sequence drives efficient protein targeting
Signal recognition particle (SRP) is a universally conserved targeting machine that mediates the targeted delivery of ∼30% of the proteome. The molecular mechanism by which eukaryotic SRP achieves efficient and selective protein targeting remains elusive. Here, we describe quantitative analyses of c...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6004459/ https://ncbi.nlm.nih.gov/pubmed/29848629 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1802252115 |
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