Filamin B represses chondrocyte hypertrophy in a Runx2/Smad3-dependent manner

FILAMIN B, which encodes a cytoplasmic actin binding protein, is mutated in several skeletal dysplasias. To further investigate how an actin binding protein influences skeletogenesis, we generated mice lacking intact Filamin B. As observed in spondylocarpotarsal synostosis syndrome patients, Filamin...

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Bibliographic Details
Main Authors: Zheng, Lihua, Baek, Hwa-Jin, Karsenty, Gerard, Justice, Monica J.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2007
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064428/
https://ncbi.nlm.nih.gov/pubmed/17606870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200703113
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