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Filamin B represses chondrocyte hypertrophy in a Runx2/Smad3-dependent manner

FILAMIN B, which encodes a cytoplasmic actin binding protein, is mutated in several skeletal dysplasias. To further investigate how an actin binding protein influences skeletogenesis, we generated mice lacking intact Filamin B. As observed in spondylocarpotarsal synostosis syndrome patients, Filamin...

詳細記述

保存先:
書誌詳細
主要な著者: Zheng, Lihua, Baek, Hwa-Jin, Karsenty, Gerard, Justice, Monica J.
フォーマット: Artigo
言語:Inglês
出版事項: The Rockefeller University Press 2007
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064428/
https://ncbi.nlm.nih.gov/pubmed/17606870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200703113
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