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Filamin B represses chondrocyte hypertrophy in a Runx2/Smad3-dependent manner
FILAMIN B, which encodes a cytoplasmic actin binding protein, is mutated in several skeletal dysplasias. To further investigate how an actin binding protein influences skeletogenesis, we generated mice lacking intact Filamin B. As observed in spondylocarpotarsal synostosis syndrome patients, Filamin...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Rockefeller University Press
2007
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2064428/ https://ncbi.nlm.nih.gov/pubmed/17606870 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200703113 |
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