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Filamin B represses chondrocyte hypertrophy in a Runx2/Smad3-dependent manner
FILAMIN B, which encodes a cytoplasmic actin binding protein, is mutated in several skeletal dysplasias. To further investigate how an actin binding protein influences skeletogenesis, we generated mice lacking intact Filamin B. As observed in spondylocarpotarsal synostosis syndrome patients, Filamin...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2064428/ https://ncbi.nlm.nih.gov/pubmed/17606870 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200703113 |
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