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Deficiency in glutamine but not glucose induces MYC-dependent apoptosis in human cells

The idea that conversion of glucose to ATP is an attractive target for cancer therapy has been supported in part by the observation that glucose deprivation induces apoptosis in rodent cells transduced with the proto-oncogene MYC, but not in the parental line. Here, we found that depletion of glucos...

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Detalhes bibliográficos
Main Authors: Yuneva, Mariia, Zamboni, Nicola, Oefner, Peter, Sachidanandam, Ravi, Lazebnik, Yuri
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064426/
https://ncbi.nlm.nih.gov/pubmed/17606868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200703099
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