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Deficiency in glutamine but not glucose induces MYC-dependent apoptosis in human cells

The idea that conversion of glucose to ATP is an attractive target for cancer therapy has been supported in part by the observation that glucose deprivation induces apoptosis in rodent cells transduced with the proto-oncogene MYC, but not in the parental line. Here, we found that depletion of glucos...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Yuneva, Mariia, Zamboni, Nicola, Oefner, Peter, Sachidanandam, Ravi, Lazebnik, Yuri
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Rockefeller University Press 2007
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064426/
https://ncbi.nlm.nih.gov/pubmed/17606868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200703099
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