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NCAM promotes assembly and activity-dependent remodeling of the postsynaptic signaling complex

The neural cell adhesion molecule (NCAM) regulates synapse formation and synaptic strength via mechanisms that have remained unknown. We show that NCAM associates with the postsynaptic spectrin-based scaffold, cross-linking NCAM with the N-methyl-d-aspartate (NMDA) receptor and Ca(2+)/calmodulin-dep...

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Detalhes bibliográficos
Main Authors: Sytnyk, Vladimir, Leshchyns'ka, Iryna, Nikonenko, Alexander G., Schachner, Melitta
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064397/
https://ncbi.nlm.nih.gov/pubmed/17000882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200604145
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