The Q(o) site of the mitochondrial complex III is required for the transduction of hypoxic signaling via reactive oxygen species production

Mammalian cells increase transcription of genes for adaptation to hypoxia through the stabilization of hypoxia-inducible factor 1α (HIF-1α) protein. How cells transduce hypoxic signals to stabilize the HIF-1α protein remains unresolved. We demonstrate that cells deficient in the complex III subunit...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Bell, Eric L., Klimova, Tatyana A., Eisenbart, James, Moraes, Carlos T., Murphy, Michael P., Budinger, G.R. Scott, Chandel, Navdeep S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Rockefeller University Press 2007
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064363/
https://ncbi.nlm.nih.gov/pubmed/17562787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200609074
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller