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Genetic analysis of β1 integrin “activation motifs” in mice
Akey feature of integrins is their ability to regulate the affinity for ligands, a process termed integrin activation. The final step in integrin activation is talin binding to the NPXY motif of the integrin β cytoplasmic domains. Talin binding disrupts the salt bridge between the α/β tails, leading...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Rockefeller University Press
2006
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2064342/ https://ncbi.nlm.nih.gov/pubmed/16954348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200604060 |
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