Genetic analysis of β1 integrin “activation motifs” in mice

Akey feature of integrins is their ability to regulate the affinity for ligands, a process termed integrin activation. The final step in integrin activation is talin binding to the NPXY motif of the integrin β cytoplasmic domains. Talin binding disrupts the salt bridge between the α/β tails, leading...

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Bibliografiska uppgifter
Huvudupphovsmän: Czuchra, Aleksandra, Meyer, Hannelore, Legate, Kyle R., Brakebusch, Cord, Fässler, Reinhard
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2006
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064342/
https://ncbi.nlm.nih.gov/pubmed/16954348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200604060
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