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Folding and organization of a contiguous chromosome region according to the gene distribution pattern in primary genomic sequence

Specific mammalian genes functionally and dynamically associate together within the nucleus. Yet, how an array of many genes along the chromosome sequence can be spatially organized and folded together is unknown. We investigated the 3D structure of a well-annotated, highly conserved 4.3-Mb region o...

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Detalhes bibliográficos
Main Authors: Shopland, Lindsay S., Lynch, Christopher R., Peterson, Kevin A., Thornton, Kathleen, Kepper, Nick, von Hase, Johann, Stein, Stefan, Vincent, Sarah, Molloy, Kelly R., Kreth, Gregor, Cremer, Christoph, Bult, Carol J., O'Brien, Timothy P.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064156/
https://ncbi.nlm.nih.gov/pubmed/16818717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200603083
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