Activation of endosomal dynein motors by stepwise assembly of Rab7–RILP–p150(Glued), ORP1L, and the receptor βlll spectrin

The small GTPase Rab7 controls late endocytic transport by the minus end–directed motor protein complex dynein–dynactin, but how it does this is unclear. Rab7-interacting lysosomal protein (RILP) and oxysterol-binding protein–related protein 1L (ORP1L) are two effectors of Rab7. We show that GTP-bou...

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Main Authors: Johansson, Marie, Rocha, Nuno, Zwart, Wilbert, Jordens, Ingrid, Janssen, Lennert, Kuijl, Coenraad, Olkkonen, Vesa M., Neefjes, Jacques
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2007
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Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2063981/
https://ncbi.nlm.nih.gov/pubmed/17283181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200606077
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