Activation of endosomal dynein motors by stepwise assembly of Rab7–RILP–p150(Glued), ORP1L, and the receptor βlll spectrin

The small GTPase Rab7 controls late endocytic transport by the minus end–directed motor protein complex dynein–dynactin, but how it does this is unclear. Rab7-interacting lysosomal protein (RILP) and oxysterol-binding protein–related protein 1L (ORP1L) are two effectors of Rab7. We show that GTP-bou...

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Главные авторы: Johansson, Marie, Rocha, Nuno, Zwart, Wilbert, Jordens, Ingrid, Janssen, Lennert, Kuijl, Coenraad, Olkkonen, Vesa M., Neefjes, Jacques
Формат: Artigo
Язык:Inglês
Опубликовано: The Rockefeller University Press 2007
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Research Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2063981/
https://ncbi.nlm.nih.gov/pubmed/17283181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200606077
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