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Nebulin-deficient mice exhibit shorter thin filament lengths and reduced contractile function in skeletal muscle
Nebulin is a giant modular sarcomeric protein that has been proposed to play critical roles in myofibrillogenesis, thin filament length regulation, and muscle contraction. To investigate the functional role of nebulin in vivo, we generated nebulin-deficient mice by using a Cre knock-in strategy. Lin...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2063916/ https://ncbi.nlm.nih.gov/pubmed/16769824 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200603119 |
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