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Distinct p53 acetylation cassettes differentially influence gene-expression patterns and cell fate

The activity of the p53 gene product is regulated by a plethora of posttranslational modifications. An open question is whether such posttranslational changes act redundantly or dependently upon one another. We show that a functional interference between specific acetylated and phosphorylated residu...

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Main Authors: Knights, Chad D., Catania, Jason, Giovanni, Simone Di, Muratoglu, Selen, Perez, Ricardo, Swartzbeck, Amber, Quong, Andrew A., Zhang, Xiaojing, Beerman, Terry, Pestell, Richard G., Avantaggiati, Maria Laura
格式: Artigo
語言:Inglês
出版: The Rockefeller University Press 2006
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2063863/
https://ncbi.nlm.nih.gov/pubmed/16717128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200512059
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