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The tumor suppressor protein p53 is required for neurite outgrowth and axon regeneration
Axon regeneration is substantially regulated by gene expression and cytoskeleton remodeling. Here we show that the tumor suppressor protein p53 is required for neurite outgrowth in cultured cells including primary neurons as well as for axonal regeneration in mice. These effects are mediated by two...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1560361/ https://ncbi.nlm.nih.gov/pubmed/16946709 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601292 |
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