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Structural damage to meiotic chromosomes impairs DNA recombination and checkpoint control in mammalian oocytes
Meiosis in human oocytes is a highly error-prone process with profound effects on germ cell and embryo development. The synaptonemal complex protein 3 (SYCP3) transiently supports the structural organization of the meiotic chromosome axis. Offspring derived from murine Sycp3 (−) (/) (−) females die...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
2006
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2063859/ https://ncbi.nlm.nih.gov/pubmed/16717125 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200512077 |
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