The activity status of cofilin is directly related to invasion, intravasation, and metastasis of mammary tumors

Understanding the mechanisms controlling cancer cell invasion and metastasis constitutes a fundamental step in setting new strategies for diagnosis, prognosis, and therapy of metastatic cancers. LIM kinase1 (LIMK1) is a member of a novel class of serine–threonine protein kinases. Cofilin, a LIMK1 su...

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Bibliografiska uppgifter
Huvudupphovsmän: Wang, Weigang, Mouneimne, Ghassan, Sidani, Mazen, Wyckoff, Jeffrey, Chen, Xiaoming, Makris, Anastasia, Goswami, Sumanta, Bresnick, Anne R., Condeelis, John S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2006
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2063840/
https://ncbi.nlm.nih.gov/pubmed/16651380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200510115
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