Estrogen transactivates EGFR via the sphingosine 1-phosphate receptor Edg-3: the role of sphingosine kinase-1

The transactivation of enhanced growth factor receptor (EGFR) by G protein–coupled receptor (GPCR) ligands is recognized as an important signaling mechanism in the regulation of complex biological processes, such as cancer development. Estrogen (E2), which is a steroid hormone that is intimately imp...

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Detaylı Bibliyografya
Asıl Yazarlar: Sukocheva, Olga, Wadham, Carol, Holmes, Andrew, Albanese, Nathaniel, Verrier, Emily, Feng, Feng, Bernal, Alex, Derian, Claudia K., Ullrich, Axel, Vadas, Mathew A., Xia, Pu
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Rockefeller University Press 2006
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2063820/
https://ncbi.nlm.nih.gov/pubmed/16636149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200506033
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