A kinase-deficient TrkC receptor isoform activates Arf6–Rac1 signaling through the scaffold protein tamalin

Neurotrophins play an essential role in mammalian development. Most of their functions have been attributed to activation of the kinase-active Trk receptors and the p75 neurotrophin receptor. Truncated Trk receptor isoforms lacking the kinase domain are abundantly expressed during development and in...

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Detalhes bibliográficos
Main Authors: Esteban, Pedro F., Yoon, Hye-Young, Becker, Jodi, Dorsey, Susan G., Caprari, Paola, Palko, Mary Ellen, Coppola, Vincenzo, Saragovi, H. Uri, Randazzo, Paul A., Tessarollo, Lino
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2006
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2063819/
https://ncbi.nlm.nih.gov/pubmed/16636148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200512013
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