CIB1 is an endogenous inhibitor of agonist-induced integrin αIIbβ3 activation

In response to agonist stimulation, the αIIbβ3 integrin on platelets is converted to an active conformation that binds fibrinogen and mediates platelet aggregation. This process contributes to both normal hemostasis and thrombosis. Activation of αIIbβ3 is believed to occur in part via engagement of...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Yuan, Weiping, Leisner, Tina M., McFadden, Andrew W., Wang, Zhengyan, Larson, Mark K., Clark, Shantres, Boudignon-Proudhon, Christel, Lam, Stephen C.-T., Parise, Leslie V.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The Rockefeller University Press 2006
विषय:
Research Articles
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2063547/
https://ncbi.nlm.nih.gov/pubmed/16418530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200505131
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