CIB1 is an endogenous inhibitor of agonist-induced integrin αIIbβ3 activation

In response to agonist stimulation, the αIIbβ3 integrin on platelets is converted to an active conformation that binds fibrinogen and mediates platelet aggregation. This process contributes to both normal hemostasis and thrombosis. Activation of αIIbβ3 is believed to occur in part via engagement of...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Yuan, Weiping, Leisner, Tina M., McFadden, Andrew W., Wang, Zhengyan, Larson, Mark K., Clark, Shantres, Boudignon-Proudhon, Christel, Lam, Stephen C.-T., Parise, Leslie V.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Rockefeller University Press 2006
Gaiak:
Research Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2063547/
https://ncbi.nlm.nih.gov/pubmed/16418530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200505131
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