Myc regulates keratinocyte adhesion and differentiation via complex formation with Miz1

Myc plays a key role in homeostasis of the skin. We show that Miz1, which mediates Myc repression of gene expression, is expressed in the epidermal basal layer. A large percentage of genes regulated by the Myc–Miz1 complex in keratinocytes encode proteins involved in cell adhesion, and some, includi...

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Main Authors: Gebhardt, Anneli, Frye, Michaela, Herold, Steffi, Benitah, Salvador Aznar, Braun, Kristin, Samans, Birgit, Watt, Fiona M., Elsässer, Hans-Peter, Eilers, Martin
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2006
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2063541/
https://ncbi.nlm.nih.gov/pubmed/16391002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200506057
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