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The interaction of Myc with Miz1 defines medulloblastoma subgroup identity
Four distinct subgroups of cerebellar medulloblastomas (MBs) differ in their histopathology, molecular profiles, and prognosis. c-Myc (Myc) or MycN overexpression in granule neuron progenitors (GNPs) induces Group 3 (G3) or Sonic Hedgehog (SHH) MBs, respectively. Differences in Myc and MycN transcri...
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| Gepubliceerd in: | Cancer Cell |
|---|---|
| Hoofdauteurs: | , , , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2016
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4714043/ https://ncbi.nlm.nih.gov/pubmed/26766587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2015.12.003 |
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