The interaction of Myc with Miz1 defines medulloblastoma subgroup identity

Four distinct subgroups of cerebellar medulloblastomas (MBs) differ in their histopathology, molecular profiles, and prognosis. c-Myc (Myc) or MycN overexpression in granule neuron progenitors (GNPs) induces Group 3 (G3) or Sonic Hedgehog (SHH) MBs, respectively. Differences in Myc and MycN transcri...

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Udgivet i:Cancer Cell
Main Authors: Vo, BaoHan T., Wolf, Elmar, Kawauchi, Daisuke, Gebhardt, Anneli, Rehg, Jerold E., Finkelstein, David, Walz, Susanne, Murphy, Brian L., Youn, Yong Ha, Han, Young-Goo, Eilers, Martin, Roussel, Martine F.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4714043/
https://ncbi.nlm.nih.gov/pubmed/26766587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2015.12.003
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