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Hypermetabolism in mice caused by the central action of an unliganded thyroid hormone receptor α1

Thyroid hormone, via its nuclear receptors TRα and TRβ, controls metabolism by acting locally in peripheral tissues and centrally by regulating sympathetic signaling. We have defined aporeceptor regulation of metabolism by using mice heterozygous for a mutant TRα1 with low affinity to T3. The animal...

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Xehetasun bibliografikoak
Egile Nagusiak: Sjögren, Maria, Alkemade, Anneke, Mittag, Jens, Nordström, Kristina, Katz, Abram, Rozell, Björn, Westerblad, Håkan, Arner, Anders, Vennström, Björn
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2007
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2063481/
https://ncbi.nlm.nih.gov/pubmed/17932484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601882
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