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Hypermetabolism in mice caused by the central action of an unliganded thyroid hormone receptor α1
Thyroid hormone, via its nuclear receptors TRα and TRβ, controls metabolism by acting locally in peripheral tissues and centrally by regulating sympathetic signaling. We have defined aporeceptor regulation of metabolism by using mice heterozygous for a mutant TRα1 with low affinity to T3. The animal...
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| Auteurs principaux: | , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2007
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2063481/ https://ncbi.nlm.nih.gov/pubmed/17932484 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601882 |
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