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Inappropriate heat dissipation ignites brown fat thermogenesis in mice with a mutant thyroid hormone receptor α1

Thyroid hormone is a major regulator of thermogenesis, acting both in peripheral organs and on central autonomic pathways. Mice heterozygous for a point mutation in thyroid hormone receptor α1 display increased thermogenesis as a consequence of high sympathetic brown fat stimulation. Surprisingly, d...

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Autori principali: Warner, Amy, Rahman, Awahan, Solsjö, Peter, Gottschling, Kristina, Davis, Benjamin, Vennström, Björn, Arner, Anders, Mittag, Jens
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3791708/
https://ncbi.nlm.nih.gov/pubmed/24046370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1310300110
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