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Unliganded thyroid hormone receptor alpha1 impairs adult hippocampal neurogenesis

Thyroid hormone regulates adult hippocampal neurogenesis, a process involved in key functions such as learning, memory and mood regulation. We addressed the role of thyroid hormone receptor TRα1 in adult hippocampal neurogenesis, using mice harboring a TRα1 null allele (TRα1−/−), overexpressing TRα1...

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Bibliografiske detaljer
Main Authors: Kapoor, Richa, van Hogerlinden, Max, Wallis, Karin, Ghosh, Himanish, Nordstrom, Kristina, Vennstrom, Bjorn, Vaidya, Vidita A.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4177098/
https://ncbi.nlm.nih.gov/pubmed/20709911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.10-161802
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