Inhibition of lymph node metastasis by an anti-angiogenic agent, TNP-470.

We assessed the inhibitory action of TNP-470 on lymph node metastasis in a metastatic model system using athymic nude mice. Mice were injected subcutaneously with 5 x 10(6) HT-1080 cells in the right groin. TNP-470 (10, 30 and 100 mg kg-1) was injected subcutaneously nine times in total every other...

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Bibliographic Details
Main Authors: Ohta, Y., Watanabe, Y., Tabata, T., Oda, M., Hayashi, Y., Endo, Y., Tanaka, M., Sasaki, T.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group|1 1997
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2063318/
https://ncbi.nlm.nih.gov/pubmed/9052402
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