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Cell cycle inhibition by the anti-angiogenic agent TNP-470 is mediated by p53 and p21(WAF1/CIP1)

Angiogenesis has been demonstrated to be essential for tumor growth and metastasis, and inhibition of angiogenesis is emerging as a promising strategy for treating cancer. Among the most potent inhibitors of angiogenesis is the fumagillin family of natural products. An analog of fumagillin, known as...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Zhang, Yi, Griffith, Eric C., Sage, Julien, Jacks, Tyler, Liu, Jun O.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2000
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC18619/
https://ncbi.nlm.nih.gov/pubmed/10841547
Tagiau: Ychwanegu Tag
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