Levels of the DNA repair enzyme human apurinic/apyrimidinic endonuclease (APE1, APEX, Ref-1) are associated with the intrinsic radiosensitivity of cervical cancers.

A study was made of the relationship between the intrinsic radiosensitivity of human cervical tumours and the expression of the DNA repair enzyme human apurinic/apyrimidinic endonuclease (HAP1). The radiosensitivity of clonogenic cells in tumour biopsies was measured as surviving fraction at 2 Gy (S...

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Main Authors: Herring, C. J., West, C. M., Wilks, D. P., Davidson, S. E., Hunter, R. D., Berry, P., Forster, G., MacKinnon, J., Rafferty, J. A., Elder, R. H., Hendry, J. H., Margison, G. P.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group|1 1998
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2062984/
https://ncbi.nlm.nih.gov/pubmed/9820167
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