Differential inactivation of mammalian and Escherichia coli O6-alkylguanine-DNA alkyltransferases by O6-benzylguanine.

Por Elder, R H, Margison, G P, Rafferty, J A
Publicado em 1994

C-terminally truncated human O6-alkylguanine-DNA alkyltransferase retains activity.

Por Elder, R H, Tumelty, J, Douglas, K T, Margison, G P, Rafferty, J A
Publicado em 1992

Influence of O(6)-benzylguanine on the anti-tumour activity and normal tissue toxicity of 1,3-bis(2-chloroethyl)-1-nitrosourea and molecular combinations of 5-fluorouracil and 2-ch...

Por Bibby, M C, Thompson, M J, Rafferty, J A, Margison, G P, McElhinney, R S
Publicado em 1999

Secretion of 72 kDa type IV collagenase/gelatinase by cultured human lipocytes. Analysis of gene expression, protein synthesis and proteinase activity.

Por Arthur, M J, Stanley, A, Iredale, J P, Rafferty, J A, Hembry, R M, Friedman, S L
Publicado em 1992

Isolation and partial characterisation of a Chinese hamster O6-alkylguanine-DNA alkyltransferase cDNA.

Por Rafferty, J A, Elder, R H, Watson, A J, Cawkwell, L, Potter, P M, Margison, G P
Publicado em 1992

Depletion of O6-alkylguanine-DNA alkyltransferase correlates with potentiation of temozolomide and CCNU toxicity in human tumour cells.

Por Baer, J. C., Freeman, A. A., Newlands, E. S., Watson, A. J., Rafferty, J. A., Margison, G. P.
Publicado em 1993

Cyclophosphamide decreases O6-alkylguanine-DNA alkyltransferase activity in peripheral lymphocytes of patients undergoing bone marrow transplantation.

Por Lee, S. M., Crowther, D., Scarffe, J. H., Dougal, M., Elder, R. H., Rafferty, J. A., Margison, G. P.
Publicado em 1992

Expression levels of the DNA repair enzyme HAP1 do not correlate with the radiosensitivities of human or HAP1-transfected rat cell lines

Por Herring, C J, Deans, B, Elder, R H, Rafferty, J A, MacKinnon, J, Barzilay, G, Hickson, I D, Hendry, J H, Margison, GP
Publicado em 1999

Immunohistological examination of the inter- and intracellular distribution of O6-alkylguanine DNA-alkyltransferase in human liver and melanoma.

Por Lee, S. M., Rafferty, J. A., Elder, R. H., Fan, C. Y., Bromley, M., Harris, M., Thatcher, N., Potter, P. M., Altermatt, H. J., Perinat-Frey, T.
Publicado em 1992

Levels of the DNA repair enzyme human apurinic/apyrimidinic endonuclease (APE1, APEX, Ref-1) are associated with the intrinsic radiosensitivity of cervical cancers.

Por Herring, C. J., West, C. M., Wilks, D. P., Davidson, S. E., Hunter, R. D., Berry, P., Forster, G., MacKinnon, J., Rafferty, J. A., Elder, R. H., Hendry, J. H., Margison, G. P.
Publicado em 1998