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Vaccinia virus temperature-sensitive mutants in the A28 gene produce non-infectious virions that bind to cells but are defective in entry

The vaccinia virus temperature-sensitive mutations Cts6 and Cts9 were mapped by marker rescue and DNA sequencing to the A28 gene. Cts6 and Cts9 contain an identical 2-bp deletion truncating the A28 protein and removing the fourth conserved cysteine near the C-terminus. Cts9 mutant virions produced a...

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Detalhes bibliográficos
Main Authors: Turner, Peter C., Dilling, Bradley P., Prins, Cindy, Cresawn, Steven G., Moyer, Richard W., Condit, Richard C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2062567/
https://ncbi.nlm.nih.gov/pubmed/17499330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2007.03.060
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