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Mapping and phenotypic analysis of spontaneous isatin-β-thiosemicarbazone resistant mutants of vaccinia virus

Treatment of wild type vaccinia virus infected cells with the anti-poxviral drug isatin-β-thiosemicarbazone (IBT) induces the viral postreplicative transcription apparatus to synthesize longer-than-normal mRNAs through an unknown mechanism. Previous studies have shown that virus mutants resistant to...

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Hlavní autoři: Cresawn, Steven G., Prins, Cindy, Latner, Donald R., Condit, Richard C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1950264/
https://ncbi.nlm.nih.gov/pubmed/17336362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2007.02.005
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