Genetic analysis of bacterial acetyltransferases: identification of amino acids determining the specificities of the aminoglycoside 6'-N-acetyltransferase Ib and IIa proteins.

The aminoglycoside 6'-N-acetyltransferase [AAC(6')-I] and AAC(6')-II enzymes represent a class of bacterial proteins capable of acetylating tobramycin, netilmicin, and 2'-N-ethylnetilmicin. However, an important difference exists in their abilities to modify amikacin and gentamic...

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Autors principals: Rather, P N, Munayyer, H, Mann, P A, Hare, R S, Miller, G H, Shaw, K J
Format: Artigo
Idioma:Inglês
Publicat: 1992
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC205986/
https://ncbi.nlm.nih.gov/pubmed/1577689
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