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Design of TATA box-binding protein/zinc finger fusions for targeted regulation of gene expression

Fusing the TATA box-binding protein (TBP) to other DNA-binding domains may provide a powerful way of targeting TBP to particular promoters. To explore this possibility, a structure-based design strategy was used to construct a fusion protein, TBP/ZF, in which the three zinc fingers of Zif268 were li...

詳細記述

保存先:
書誌詳細
主要な著者: Kim, Jin-Soo, Kim, Jaesang, Cepek, Karyn L., Sharp, Phillip A., Pabo, Carl O.
フォーマット: Artigo
言語:Inglês
出版事項: The National Academy of Sciences of the USA 1997
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC20489/
https://ncbi.nlm.nih.gov/pubmed/9108026
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