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Circulating blood leukocyte gene expression profiles: Effects of the Ames dwarf mutation on pathways related to immunity and inflammation

Aging is associated with a decline of immune competence and an increase in markers of inflammation. There is considerable evidence that inflammatory processes play a role in aging and the determination of lifespan. Hypopituitary Ames dwarf mice have extended longevity and exhibit many symptoms of de...

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Autors principals: Dhahbi, Joseph, Li, Xichen, Tran, Tim, Masternak, Michal M., Bartke, Andrzej
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045642/
https://ncbi.nlm.nih.gov/pubmed/17611063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2007.04.004
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