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Chemoimmunotherapy of Chronic Hepatitis B Virus Infection in the Woodchuck Model Overcomes Immunologic Tolerance and Restores T-Cell Responses to Pre-S and S Regions of the Viral Envelope Protein
Treatment of chronic hepatitis B virus (HBV) infection could combine potent antiviral drugs and therapeutic vaccines to overcome immunological tolerance and induce the recovery phenotype to protect against disease progression. Conventional vaccination of woodchucks chronically infected with the wood...
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Hoofdauteurs: | , , , |
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Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
American Society for Microbiology
2007
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2045479/ https://ncbi.nlm.nih.gov/pubmed/17652398 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00691-07 |
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