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Chemoimmunotherapy of Chronic Hepatitis B Virus Infection in the Woodchuck Model Overcomes Immunologic Tolerance and Restores T-Cell Responses to Pre-S and S Regions of the Viral Envelope Protein

Treatment of chronic hepatitis B virus (HBV) infection could combine potent antiviral drugs and therapeutic vaccines to overcome immunological tolerance and induce the recovery phenotype to protect against disease progression. Conventional vaccination of woodchucks chronically infected with the wood...

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Main Authors: Menne, Stephan, Tennant, Bud C., Gerin, John L., Cote, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045479/
https://ncbi.nlm.nih.gov/pubmed/17652398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00691-07
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